Showing 1 - 20 of 623

Incorporating genetic data improves target trial emulations and informs the use of polygenic scores in randomized controlled trial design
Jakob German ; Zhiyu Yang ; Sarah Urbut ; et al.
Nat Genet
Nature genetics, vol. 57, no. 7, pp. 1620-1627

Methodologies for network meta-analysis of randomised controlled trials in pain, anaesthesia, and perioperative medicine: a narrative review: a narrative review
Brett Doleman ; Janus Christian Jakobsen ; Ole Mathiesen ; et al.
Br J Anaesth
Doleman, B, Jakobsen, J C, Mathiesen, O, Cooper, N, Sutton, A & Hardman, J 2025, ' Methodologies for network meta-analysis of randomised controlled trials in pain, anaesthesia, and perioperative medicine : a narrative review ', British Journal of Anaesthesia, vol. 134, no. 4, pp. 1029-1040 . https://doi.org/10.1016/j.bja.2024.12.039

The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial
Gaskell, Charlotte ; Linton, Kim ; Bishton, Mark ; et al.
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 25, Iss 1, Pp 1-8 (2025)
Gaskell, C, Linton, K, Bishton, M, McIlroy, G, Lax, S, Fox, S, Hopkins, L, Collings, R, Rhodes, M, Seale, T & Jackson, A 2025, 'The REFRACT trial : implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial', BMC Medical Research Methodology, vol. 25, no. 1, pp. 121. https://doi.org/10.1186/s12874-025-02575-5

Rethinking the Gold Standard of Randomized Controlled Trials in Education
Orione, Luis ; Orione, Luis

Sample size recalculation based on the overall success rate in a randomized test-treatment trial with restricting randomization to discordant pairs
Elzner, Caroline ; Pepić, Amra ; Gerke, Oke ; et al.
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 25, Iss 1, Pp 1-13 (2025)

Designing and Evaluating Bayesian Advanced Adaptive Randomised Clinical Trials:A Practical Guide
Granholm, Anders ; Jensen, Aksel Karl Georg ; Lange, Theis ; et al.
Granholm, A, Jensen, A K G, Lange, T, Perner, A, Møller, M H & Kaas-Hansen, B S 2025, ' Designing and Evaluating Bayesian Advanced Adaptive Randomised Clinical Trials : A Practical Guide ', Pharmaceutical Statistics, vol. 24, no. 6, e70042 . https://doi.org/10.1002/pst.70042

Assessing the comparative effects of interventions in COPD: a tutorial on network meta-analysis for clinicians
Katrin Haeussler ; Afisi S. Ismaila ; Mia Malmenäs ; et al.
Respir Res
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)

Effectiveness of preoperative ketamine gargle to reduce postoperative sore throat in adult patients undergoing surgery with endotracheal tube; systematic review and meta-analysis of randomized control trials
Molla Amsalu Tadesse ; Agmuas Asichale Alimawu ; Fetene Seyoum Kebede ; et al.
BMC Anesthesiol
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-14 (2024)

Mortality in septic patients treated with short-acting betablockers: a comprehensive meta-analysis of randomized controlled trials
Alexandru, Mihai-Gabriel ; Niewald, Patrick ; Krüger, Stefan ; et al.
Crit Care

Exploring the characteristics, methods and reporting of systematic reviews with meta-analyses of time-to-event outcomes: a meta-epidemiological study
Goldkuhle, Marius ; Hirsch, Caroline ; Iannizzi, Claire ; et al.
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)

Endovascular treatment of peripheral arterial disease:Endo-STAR framework for the design, conduct, and reporting of trials
Zywicka, Ewa M ; Moore, Andrew J ; Twine, Christopher ; et al.
Zywicka, E M, Moore, A J, Twine, C, Behrendt, C-A, Bosiers, M, Brodmann, M, Choke, E, deBorst, G J, Diamantopoulos, A, Enzmann, F, Farber, A, Ansel, G, Gattuso, D, Goh, G S, Yann, G, Jansen, S, Landini, M, Lejay, A, Lichtenberg, M, Menard, M, Mezes, P, Mills, J, Nixon, J, Nordanstig, J, O'Connell, K, Ozdemir, B, Patrone, L, Puppala, S, Saratzis, A, Secemsky, E A, Sigrid, N, Stavroulakis, K, Steiner, S, Teraa, M, Van Herzeele, I, Venermo, M, Zeller, T, Mouton, R & Hinchliffe, R J 2025, 'Endovascular treatment of peripheral arterial disease : Endo-STAR framework for the design, ....

Randomized Trials in Cardiac Surgery: Why and How
Gaudino, M. ; Siepe, M. ; Murphy, G.J. ; et al.

Optimizing clinical scientific research:the cohort intervention random sampling study with historical controls
de Klerk, Nadine D. ; Berben, Phebe B.Q. ; van der Ven, Myrthe ; et al.
de Klerk, N D, Berben, P B Q, van der Ven, M, Fransen, A F, van der Hout-van der Jagt, M B, Oei, S G, van Laar, J O H E & van den Heuvel, E R 2025, 'Optimizing clinical scientific research : the cohort intervention random sampling study with historical controls', Journal of Comparative Effectiveness Research, vol. 14, no. 11, e240168. https://doi.org/10.57264/cer-2024-0168

A comparison of frequentist and Bayesian approaches to the Personalised Randomised Controlled Trial (PRACTical)—design and analysis considerations
Jackson, Holly ; Shou, Yiyun ; Azad, Nur Amira Binte Mohamed ; et al.
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 25, Iss 1, Pp 1-14 (2025)

Forced randomization: the what, why, and how
Carter, Kerstine ; Kuznetsova, Olga ; Anisimov, Volodymyr ; et al.
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-22 (2024)

The effectiveness of unsupervised home-based exercise for improving lower extremity physical function in older adults in Western and Eastern cultures: a systematic review and meta-analysis
Liang, Ian Ju ; Perkin, Oliver J. ; McGuigan, Polly M. ; et al.
BMC Geriatr
BMC Geriatrics, Vol 24, Iss 1, Pp 1-11 (2024)

The impact of allocation bias on test decisions in clinical trials with multiple endpoints using multiple testing strategies
Schoenen, Stefanie ; Heussen, Nicole ; Verbeeck, Johan ; et al.
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-14 (2024)
BMC medical research methodology 24(1), 223 (2024). doi:10.1186/s12874-024-02335-x

Evaluation of the Fill-it-up-design to use historical control data in randomized clinical trials with two arm parallel group design
Wied, Stephanie ; Posch, Martin ; Hilgers, Ralf-Dieter
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-16 (2024)
BMC medical research methodology 24, 197 (2024). doi:10.1186/s12874-024-02306-2

Clinical trials with mechanism evaluation of intervention(s): mind the power and sample size calculation
Kim May Lee ; Jennifer Hellier ; Richard Emsley
Trials
Trials, Vol 25, Iss 1, Pp 1-6 (2024)

crossnma: An R package to synthesize cross-design evidence and cross-format data using network meta-analysis and network meta-regression
Hamza, Tasnim A. A. ; Schwarzer, Guido ; Salanti, Georgia
BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-16 (2024)
Hamza, Tasnim; Schwarzer, Guido; Salanti, Georgia (2024). crossnma: An R package to synthesize cross-design evidence and cross-format data using network meta-analysis and network meta-regression. BMC Medical research methodology, 24(169) BioMed Central 10.1186/s12874-023-02130-0 <http://dx.doi.org/10.1186/s12874-023-02130-0>
Hamza, Tasnim; Schwarzer, Guido; Salanti, Georgia (2024). crossnma: An R package to synthesize cross-design evidence and cross-format data using network meta-analysis and network meta-regression. BMC Medical research methodology, 24(1), p. 169. BioMed Central 10.1186/s12874-023-02130-0 <http://dx.doi.org/10.1186/s12874-023-02130-0>