Serviceeinschränkungen vom 12.-22.02.2026 - weitere Infos auf der UB-Homepage

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21

Glutamate ionotropic receptor NMDA type subunit 1: A novel potential protein target of dapagliflozin against renal interstitial fibrosis
Liu, Yuyuan ; Wang, Yanzhe ; Chen, Sijia ; et al.
In European Journal of Pharmacology 15 March 2023 943

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22

Ustiloxins induce kidney injury via the TLR2/MAPK/NF-κB pathway
Du, Yingchun ; Zhang, Guomei ; Zhou, Xuming ; et al.
In Toxicon December 2025 268

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23

Innovative insights: ITLN1 modulates renal injury in response to radiation
He, Peng ; Guo, Ying ; Wang, Shize ; et al.
In International Immunopharmacology 30 May 2024 133

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24

EHP-101 alleviates angiotensin II-induced fibrosis and inflammation in mice
García-Martín, Adela ; Navarrete, Carmen ; Garrido-Rodríguez, Martin ; et al.
In Biomedicine & Pharmacotherapy October 2021 142

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25

The critical role of endoplasmic reticulum stress and the stimulator of interferon genes (STING) pathway in kidney fibrosis
Andrade-Silva, Magaiver ; Dhillon, Poonam ; Sanchez-Navarro, Andrea ; et al.
In Kidney International February 2025 107(2):302-316

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26

Urine Single-Cell RNA Sequencing in Focal Segmental Glomerulosclerosis Reveals Inflammatory Signatures
Latt, Khun Zaw ; Heymann, Jurgen ; Jessee, Joseph H. ; et al.
In Kidney International Reports February 2022 7(2):289-304

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27

Inflammatory cytokines drive local C3 transcription to regulate metabolic reprogramming in kidney epithelial cells and subsequent fibrosis
Freiwald, Tilo ; Tajmul, Md ; Trujillo-Ochoa, Jorge-Luis ; et al.
In Immunobiology July 2025 230(4)

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28

Exploring kidney allograft rejection: A proof-of-concept study using spatial transcriptomics
Martin-Martin, Cristina ; Suarez-Alvarez, Beatriz ; González, Monika ; et al.
In American Journal of Transplantation July 2024 24(7):1161-1171

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29

POS0074 TRANSCRIPTOMIC PROFILING OF KIDNEY BIOPSIES IMPLICATES Th17 AND IL-17 IN ANCA-ASSOCIATED GLOMERULONEPHRITIS
Stojkic, I. ; Arazi, A. ; Song, H. ; et al.
In Annals of the Rheumatic Diseases June 2025 84 Supplement 1:379-380

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30

Identification of Diabetic Nephropathy Biomarkers Through Transcriptomics
Identification of Diabetic Nephropathy Biomarkers Through Transcriptomics
American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010 Jan;33 Suppl 1(Suppl 1):S62-9. doi: 10.2337/dc10-S062. No abstract available.
Gonzalez-Villalpando C, Davila-Cervantes CA, Zamora-Macorra M, Trejo-Valdivia B, Gonzalez-Villalpando ME. Incidence of type 2 diabetes in Mexico: results of the Mexico City Diabetes Study after 18 years of follow-up. Salud Publica Mex. 2014 Jan-Feb;56(1):11-7. doi: 10.21149/spm.v56i1.7318.
Secretaría de Salud. Instituto Nacional de Salud Pública. Encuesta Nacional de Salud y Nutrición 2012. 2012
American Diabetes Association. Standards of medical care in diabetes--2014. Diabetes Care. 2014 Jan;37 Suppl 1:S14-80. doi: 10.2337/dc14-S014. No abstract available.
Vora JP, Ibrahim HA, Bakris GL. Responding to the challenge of diabetic nephropathy: the historic evolution of detection, prevention and management. J Hum Hypertens. 2000 Oct-Nov;14(10-11):667-85. doi: 10.1038/sj.jhh.1001058.
Benjamín; T-D, Antonio; M-MM, Eugenia; C-PM, A D-EMT, Lucia; r-D, Patricia; R-C, et al. DETECCIÓN DE MICROALBUMINURIA EN PACIENTES DIABÉTICOS TIPO II. Bioquimia. 2007(SA126)
Cueto-Manzano AM, Cortes-Sanabria L, Martinez-Ramirez HR, Rojas-Campos E, Barragan G, Alfaro G, Flores J, Anaya M, Canales-Munoz JL. Detection of early nephropathy in Mexican patients with type 2 diabetes mellitus. Kidney Int Suppl. 2005 Aug;(97):S40-5. doi: 10.1111/j.1523-1755.2005.09707.x.
Bello-Chavolla OY, Rojas-Martinez R, Aguilar-Salinas CA, Hernandez-Avila M. Epidemiology of diabetes mellitus in Mexico. Nutr Rev. 2017 Jan;75(suppl 1):4-12. doi: 10.1093/nutrit/nuw030.
Gheith O, Farouk N, Nampoory N, Halim MA, Al-Otaibi T. Diabetic kidney disease: world wide difference of prevalence and risk factors. J Nephropharmacol. 2015 Oct 9;5(1):49-56. eCollection 2016.
Tziomalos K, Athyros VG. Diabetic Nephropathy: New Risk Factors and Improvements in Diagnosis. Rev Diabet Stud. 2015 Spring-Summer;12(1-2):110-8. doi: 10.1900/RDS.2015.12.110. Epub 2015 Aug 10.
Zenteno-Castillo P, Munoz-Lopez DB, Merino-Reyes B, Vega-Sanchez A, Preciado-Puga M, Gonzalez-Yebra AL, Kornhauser C. Prevalence of diabetic nephropathy in Type 2 Diabetes Mellitus in rural communities of Guanajuato, Mexico. Effect after 6 months of Telmisartan treatment. J Clin Transl Endocrinol. 2015 Aug 18;2(4):125-128. doi: 10.1016/j.jcte.2015.08.001. eCollection 2015 Dec.
American Diabetes Association. Standards of medical care in diabetes--2010. Diabetes Care. 2010 Jan;33 Suppl 1(Suppl 1):S11-61. doi: 10.2337/dc10-S011. No abstract available.
Slocum JL, Heung M, Pennathur S. Marking renal injury: can we move beyond serum creatinine? Transl Res. 2012 Apr;159(4):277-89. doi: 10.1016/j.trsl.2012.01.014. Epub 2012 Feb 3.
National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002 Feb;39(2 Suppl 1):S1-266. No abstract available.
Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function--measured and estimated glomerular filtration rate. N Engl J Med. 2006 Jun 8;354(23):2473-83. doi: 10.1056/NEJMra054415. No abstract available.
Stevens LA, Levey AS. Measurement of kidney function. Med Clin North Am. 2005 May;89(3):457-73. doi: 10.1016/j.mcna.2004.11.009.
Levin A, Stevens PE. Summary of KDIGO 2012 CKD Guideline: behind the scenes, need for guidance, and a framework for moving forward. Kidney Int. 2014 Jan;85(1):49-61. doi: 10.1038/ki.2013.444. Epub 2013 Nov 27.
de Boer IH, Rue TC, Cleary PA, Lachin JM, Molitch ME, Steffes MW, Sun W, Zinman B, Brunzell JD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group; White NH, Danis RP, Davis MD, Hainsworth D, Hubbard LD, Nathan DM. Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort. Arch Intern Med. 2011 Mar 14;171(5):412-20. doi: 10.1001/archinternmed.2011.16.
Hovind P, Tarnow L, Rossing P, Jensen BR, Graae M, Torp I, Binder C, Parving HH. Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: inception cohort study. BMJ. 2004 May 8;328(7448):1105. doi: 10.1136/bmj.38070.450891.FE. Epub 2004 Apr 19.
Vaidya VS, Niewczas MA, Ficociello LH, Johnson AC, Collings FB, Warram JH, Krolewski AS, Bonventre JV. Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-beta-D-glucosaminidase. Kidney Int. 2011 Feb;79(4):464-70. doi: 10.1038/ki.2010.404. Epub 2010 Oct 27.
Perkins BA, Ficociello LH, Silva KH, Finkelstein DM, Warram JH, Krolewski AS. Regression of microalbuminuria in type 1 diabetes. N Engl J Med. 2003 Jun 5;348(23):2285-93. doi: 10.1056/NEJMoa021835.
Kramer HJ, Nguyen QD, Curhan G, Hsu CY. Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus. JAMA. 2003 Jun 25;289(24):3273-7. doi: 10.1001/jama.289.24.3273.
MacIsaac RJ, Tsalamandris C, Panagiotopoulos S, Smith TJ, McNeil KJ, Jerums G. Nonalbuminuric renal insufficiency in type 2 diabetes. Diabetes Care. 2004 Jan;27(1):195-200. doi: 10.2337/diacare.27.1.195.
Napierala JS, Li Y, Lu Y, Lin K, Hauser LA, Lynch DR, Napierala M. Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers. Dis Model Mech. 2017 Nov 1;10(11):1353-1369. doi: 10.1242/dmm.030536.
Wang Z, Gerstein M, Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet. 2009 Jan;10(1):57-63. doi: 10.1038/nrg2484.
Zhang ZH, Jhaveri DJ, Marshall VM, Bauer DC, Edson J, Narayanan RK, Robinson GJ, Lundberg AE, Bartlett PF, Wray NR, Zhao QY. A comparative study of techniques for differential expression analysis on RNA-Seq data. PLoS One. 2014 Aug 13;9(8):e103207. doi: 10.1371/journal.pone.0103207. eCollection 2014.
Oshlack A, Robinson MD, Young MD. From RNA-seq reads to differential expression results. Genome Biol. 2010;11(12):220. doi: 10.1186/gb-2010-11-12-220. Epub 2010 Dec 22.
Li P, Piao Y, Shon HS, Ryu KH. Comparing the normalization methods for the differential analysis of Illumina high-throughput RNA-Seq data. BMC Bioinformatics. 2015 Oct 28;16:347. doi: 10.1186/s12859-015-0778-7.
O'Connell PJ, Zhang W, Menon MC, Yi Z, Schroppel B, Gallon L, Luan Y, Rosales IA, Ge Y, Losic B, Xi C, Woytovich C, Keung KL, Wei C, Greene I, Overbey J, Bagiella E, Najafian N, Samaniego M, Djamali A, Alexander SI, Nankivell BJ, Chapman JR, Smith RN, Colvin R, Murphy B. Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study. Lancet. 2016 Sep 3;388(10048):983-93. doi: 10.1016/S0140-6736(16)30826-1. Epub 2016 Jul 22.
Ju W, Nair V, Smith S, Zhu L, Shedden K, Song PXK, Mariani LH, Eichinger FH, Berthier CC, Randolph A, Lai JY, Zhou Y, Hawkins JJ, Bitzer M, Sampson MG, Thier M, Solier C, Duran-Pacheco GC, Duchateau-Nguyen G, Essioux L, Schott B, Formentini I, Magnone MC, Bobadilla M, Cohen CD, Bagnasco SM, Barisoni L, Lv J, Zhang H, Wang HY, Brosius FC, Gadegbeku CA, Kretzler M; ERCB, C-PROBE, NEPTUNE, and PKU-IgAN Consortium. Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker. Sci Transl Med. 2015 Dec 2;7(316):316ra193. doi: 10.1126/scitranslmed.aac7071.
Trzybulska D, Eckersten D, Giwercman A, Christensson A, Tsatsanis C. Alterations in Serum MicroRNA Profile During Hemodialysis - Potential Biological Implications. Cell Physiol Biochem. 2018;46(2):793-801. doi: 10.1159/000488737. Epub 2018 Mar 29.
Viloria; AT, Castillo RZ. Nefropatía diabética. Rev Hosp Gral Dr M Gea González. 2002;5(1 and 2):24-32

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31

Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis
Handin, Niklas ; Yuan, Di ; Ölander, Magnus ; et al.
In Computational and Structural Biotechnology Journal 2023 21:4361-4369

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32

Multi-omics Study of Peritoneal Dialysis Effluent to Explore Biomarkers of Peritoneal Fibrosis
Na Jiang, doctor
Multi-omics Study of Peritoneal Dialysis Effluent to Explore Biomarkers of Peritoneal Fibrosis

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33

Analysis of extracellular matrix dynamics in renal fibrosis: towards discovering new therapeutic targets and biomarkers
Rende, Umut

kidney fibrosis chronic kidney disease mouse kidneys proteomics of mouse kedn... transcriptomics of mouse... tubulointerstitial fibro...
Dissertation
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35

Sex-specific proximal tubular cell differentiation pathways identified by single-nucleus RNA sequencing.
Lu YA ; Smith T ; Deshpande S ; et al.
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Animals Female Male Mice Cell Proliferation Transcriptome
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36

Whole-transcriptome sequencing reveals key biomarkers and pathways in renal fibrosis
Bai, Jingya ; Pei, Shuyan ; Zhang, Jianfeng ; et al.
Discover Medicine. 2(1)

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38

Axl‐inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model.
Hoel, August ; Osman, Tarig ; Hoel, Fredrik ; et al.
Journal of Cellular & Molecular Medicine; Aug2021, Vol. 25 Issue 15, p7407-7417, 11p

URETERIC obstruction RENAL fibrosis KREBS cycle PROTEIN-tyrosine kinase... FATTY acid oxidation PLANT mitochondria
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39

Demethylzeylasteral protects against renal interstitial fibrosis by attenuating mitochondrial complex I-mediated oxidative stress.
Shen, Pan ; Deng, Xuan ; Li, Tingting ; et al.
Journal of Ethnopharmacology. Jun2024, Vol. 327, pN.PAG-N.PAG. 1p.

TRITERPENES MITOCHONDRIA OXIDATIVE stress DESCRIPTIVE statistics FIBROSIS IMMUNOHISTOCHEMISTRY
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40

Single-cell transcriptomic analysis reveals the association of Ccl6+Ccr2+Arg1+ macrophages with renal interstitial fibrosis in AKI.
Zheng, Xin ; Wang, Jiayu ; Chen, Weinan ; et al.
PLoS ONE; 9/15/2025, Vol. 20 Issue 9, p1-23, 23p

RENAL fibrosis MACROPHAGES TRANSCRIPTOMES ACUTE kidney failure ARGINASE CHEMOKINES
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