Treffer: Simulating genetic networks made easy: network construction with simple building blocks.

Title:
Simulating genetic networks made easy: network construction with simple building blocks.
Authors:
Vercruysse S; Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University Technologiepark 927, B-9052, Gent, Belgium., Kuiper M
Source:
Bioinformatics (Oxford, England) [Bioinformatics] 2005 Jan 15; Vol. 21 (2), pp. 269-71. Date of Electronic Publication: 2004 Aug 19.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
Language:
English
Journal Info:
Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1367-4803 (Print) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE
Imprint Name(s):
Original Publication: Oxford : Oxford University Press, c1998-
MeSH Terms:
Algorithms* , Computer Simulation* , Models, Genetic* , User-Computer Interface*, Gene Expression Regulation/*physiology , Signal Transduction/*physiology , Transcription Factors/*metabolism, Internet ; Programming Languages ; Software
Substance Nomenclature:
0 (Transcription Factors)
Entry Date(s):
Date Created: 20040821 Date Completed: 20050308 Latest Revision: 20130520
Update Code:
20250114
DOI:
10.1093/bioinformatics/bth478
PMID:
15319258
Database:
MEDLINE

Weitere Informationen

Unlabelled: We present SIM-plex, a genetic network simulator with a very intuitive interface in which a user can easily specify interactions as simple 'if-then' statements. The simulator is based on the mathematical model of Piecewise Linear Differential Equations (PLDEs). With PLDEs, genetic interactions are approximated as acting in a switch-like manner.
Availability: The Java program, examples and a tutorial are available at http://www.psb.ugent.be/cbd/
Contact: {stcru,makui}@psb.ugent.be