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Treffer: An evolved interpretation of Austin Bradford Hill's causal viewpoints and their influence on epidemiologic methods.

Title:
An evolved interpretation of Austin Bradford Hill's causal viewpoints and their influence on epidemiologic methods.
Authors:
Lesko CR; Department of Epidemiology, Johns Hopkins University, Baltimore, MD, United States., Fox MP; Departments of Epidemiology & Global Health, Boston University, Boston, MA, United States.
Source:
American journal of epidemiology [Am J Epidemiol] 2025 Jun 03; Vol. 194 (6), pp. 1476-1481.
Publication Type:
Journal Article; Historical Article
Language:
English
Journal Info:
Publisher: Oxford University Press Country of Publication: United States NLM ID: 7910653 Publication Model: Print Cited Medium: Internet ISSN: 1476-6256 (Electronic) Linking ISSN: 00029262 NLM ISO Abbreviation: Am J Epidemiol Subsets: MEDLINE
Imprint Name(s):
Publication: Cary, NC : Oxford University Press
Original Publication: Baltimore, School of Hygiene and Public Health of Johns Hopkins Univ.
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Grant Information:
K01 AA028193 United States AA NIAAA NIH HHS; K01 AA028193 United States NH NIH HHS
Contributed Indexing:
Keywords: causality; epistemology; induction
Entry Date(s):
Date Created: 20240917 Date Completed: 20250603 Latest Revision: 20250922
Update Code:
20250922
PubMed Central ID:
PMC12133282
DOI:
10.1093/aje/kwae367
PMID:
39289169
Database:
MEDLINE

Weitere Informationen

In 1965, Sir Austin Bradford Hill articulated nine viewpoints for evaluating whether a body of evidence about the relationship between an exposure and outcome should be interpreted causally. In this commentary, we highlight a selection of the ways in which these viewpoints have had an impact on the field of epidemiology in terms of methods development, study design, and interpretation of results. Additionally, we opine on how the viewpoints relate to our understanding of basic epidemiologic concepts-for example, our choice of absolute or relative measures of effect, our evolving understanding of the role of context in the generalizability of study results, and modern epistemologies for causal inference (ie, the potential outcomes framework and graphical causal models). Hill cautioned his audience that evidence should be weighed according to the policy choice it would inform and the context in which that policy would be implemented. We root our remarks in considerations of the public health impact of our conclusions about the causal nature of an observed relationship.
(© The Author(s) 2024. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)