Result: Eleven-Year Report of High Number of Diphtheria Cases in Children in East Java Province, Indonesia.
Title:
Eleven-Year Report of High Number of Diphtheria Cases in Children in East Java Province, Indonesia.
Authors:
Husada D; Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Hartini Y; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Nuringhati KW; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Tindage SG; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Mustikasari RI; Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Kartina L; Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Puspitasari D; Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Basuki PS; Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Moedjito I; Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia., Zumaroh Z; East Java Provincial Health Office, Surabaya 60231, Indonesia., Susanto H; East Java Provincial Health Office, Surabaya 60231, Indonesia., Wulandari W; East Java Provincial Health Office, Surabaya 60231, Indonesia., Anggraini SD; East Java Provincial Health Office, Surabaya 60231, Indonesia., Triyono EA; East Java Provincial Health Office, Surabaya 60231, Indonesia.; Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya 60115, Indonesia.; Department of Internal Medicine, Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia.
Source:
Tropical medicine and infectious disease [Trop Med Infect Dis] 2024 Sep 07; Vol. 9 (9). Date of Electronic Publication: 2024 Sep 07.
Publication Type:
Journal Article
Language:
English
Journal Info:
Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101709042 Publication Model: Electronic Cited Medium: Internet ISSN: 2414-6366 (Electronic) Linking ISSN: 24146366 NLM ISO Abbreviation: Trop Med Infect Dis Subsets: PubMed not MEDLINE
Imprint Name(s):
Original Publication: Basel, Switzerland : MDPI AG, [2016]-
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Cureus. 2024 Mar 22;16(3):e56744. (PMID: 38650814)
Hum Vaccin Immunother. 2023 Aug 1;19(2):2219577. (PMID: 37291691)
Southeast Asian J Trop Med Public Health. 2014 Sep;45(5):1132-41. (PMID: 25417516)
Nat Rev Dis Primers. 2019 Dec 5;5(1):81. (PMID: 31804499)
Infect Disord Drug Targets. 2024;24(4):20-28. (PMID: 38018182)
Nat Rev Microbiol. 2023 Mar;21(3):195-210. (PMID: 36253478)
J Infect Dev Ctries. 2022 Jul 28;16(7):1159-1165. (PMID: 35905020)
MMWR Morb Mortal Wkly Rep. 2021 Jul 23;70(29):1013-1019. (PMID: 34292924)
Clin Infect Dis. 2020 Jun 24;71(1):89-97. (PMID: 31425581)
Confl Health. 2019 May 22;13:19. (PMID: 31139250)
J Infect. 2024 May;88(5):106141. (PMID: 38513739)
PLoS One. 2015 Apr 24;10(4):e0121749. (PMID: 25909365)
Lancet. 2019 Mar 23;393(10177):1254-1260. (PMID: 30871722)
Nat Commun. 2024 Apr 20;15(1):3374. (PMID: 38643200)
Cureus. 2023 Mar 4;15(3):e35769. (PMID: 37025722)
Euro Surveill. 2014 Jun 19;19(24):. (PMID: 24970373)
Pan Afr Med J. 2023 Aug 28;45:186. (PMID: 38020360)
Emerg Infect Dis. 2019 Oct;25(10):1834-1842. (PMID: 31538559)
Viruses. 2023 Jan 13;15(1):. (PMID: 36680263)
BMC Med. 2019 Mar 12;17(1):58. (PMID: 30857521)
Cureus. 2024 Mar 13;16(3):e56093. (PMID: 38618353)
Lancet Infect Dis. 2024 Feb;24(2):e87. (PMID: 38280399)
Acta Med Indones. 2019 Jul;51(3):205-213. (PMID: 31699943)
J Travel Med. 2019 Jan 1;26(1):. (PMID: 30407562)
Emerg Infect Dis. 2018 Jul;24(7):1340-1344. (PMID: 29912686)
Lancet Glob Health. 2022 Feb;10(2):e186-e194. (PMID: 34951973)
Sci Rep. 2021 Mar 18;11(1):6378. (PMID: 33737710)
Pediatr Infect Dis J. 2015 Nov;34(11):1152-6. (PMID: 26226444)
Lancet. 2024 Jun 15;403(10444):2590-2591. (PMID: 38879248)
J Family Med Prim Care. 2022 Nov;11(11):7163-7167. (PMID: 36993015)
Turk J Med Sci. 2020 Apr 15;50(SI-1):571-577. (PMID: 32293835)
Pan Afr Med J. 2018 Dec 27;31:249. (PMID: 31448005)
Immun Inflamm Dis. 2023 Nov;11(11):e1096. (PMID: 38018582)
Glob Epidemiol. 2023 Feb 21;5:100100. (PMID: 37638375)
Hum Vaccin Immunother. 2020 Sep 1;16(9):2144-2150. (PMID: 32692596)
Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30547-30553. (PMID: 33168723)
Emerg Infect Dis. 2018 Nov;24(11):2084-2086. (PMID: 30334727)
Emerg Infect Dis. 1998 Oct-Dec;4(4):539-50. (PMID: 9866730)
Cureus. 2024 Mar 22;16(3):e56744. (PMID: 38650814)
Hum Vaccin Immunother. 2023 Aug 1;19(2):2219577. (PMID: 37291691)
Southeast Asian J Trop Med Public Health. 2014 Sep;45(5):1132-41. (PMID: 25417516)
Nat Rev Dis Primers. 2019 Dec 5;5(1):81. (PMID: 31804499)
Infect Disord Drug Targets. 2024;24(4):20-28. (PMID: 38018182)
Nat Rev Microbiol. 2023 Mar;21(3):195-210. (PMID: 36253478)
J Infect Dev Ctries. 2022 Jul 28;16(7):1159-1165. (PMID: 35905020)
MMWR Morb Mortal Wkly Rep. 2021 Jul 23;70(29):1013-1019. (PMID: 34292924)
Clin Infect Dis. 2020 Jun 24;71(1):89-97. (PMID: 31425581)
Confl Health. 2019 May 22;13:19. (PMID: 31139250)
J Infect. 2024 May;88(5):106141. (PMID: 38513739)
PLoS One. 2015 Apr 24;10(4):e0121749. (PMID: 25909365)
Lancet. 2019 Mar 23;393(10177):1254-1260. (PMID: 30871722)
Nat Commun. 2024 Apr 20;15(1):3374. (PMID: 38643200)
Cureus. 2023 Mar 4;15(3):e35769. (PMID: 37025722)
Euro Surveill. 2014 Jun 19;19(24):. (PMID: 24970373)
Pan Afr Med J. 2023 Aug 28;45:186. (PMID: 38020360)
Contributed Indexing:
Keywords: East Java province; Indonesia; adolescent; children; communicable disease; diphtheria; surveillance; vaccine-preventable disease
Entry Date(s):
Date Created: 20240927 Latest Revision: 20240929
Update Code:
20250114
PubMed Central ID:
PMC11435498
DOI:
10.3390/tropicalmed9090204
PMID:
39330893
Database:
MEDLINE
Further Information
A high incidence of diphtheria cases in children in East Java province, Indonesia, has been observed since the beginning of this century. Despite many efforts, the outbreaks continue. This study aims to explain the high incidence of diphtheria in children in East Java province since 2013. This cross-sectional surveillance report-based study used data from 38 districts in East Java since 1 January 2013. Collected data included demographics, clinical information, additional examinations, immunization history, and close contact management. Over eleven years, there were 4009 diphtheria patients, of whom 2921 (72.86%) were under 18 years of age. Boys (59.77%) outnumbered girls, and the most common age category was >60-144 months (51.66%). Most cases had incomplete or zero immunization (76.16%). Tonsillopharyngeal diphtheria was the most common type (69.60%). The five top districts with the most cases were Surabaya, Sidoarjo, Kabupaten Blitar, Kota Malang, and Kabupaten Malang. The eleven-year case fatality rate (CFR) was 2.36% (69/2921). This study shows that diphtheria cases in children and adolescents in East Java have consistently been high, and low immunization coverage might still be the leading cause. There has also been a shift in the district distribution. Diphtheria outbreaks require complete and sustainable efforts, not just outbreak response immunizations.