• ABGCEPD for acute symptomatic...

Treffer: ABGCEPD for acute symptomatic isolated cervical internal carotid artery occlusion to improve reperfusion and reduce distal embolization.

Title:
ABGCEPD for acute symptomatic isolated cervical internal carotid artery occlusion to improve reperfusion and reduce distal embolization.
Authors:
Li J; Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin Medical University, Tianjin, 300070, China.; Tianjin Key Laboratory of Neurotrauma Repair, Characteristic Medical Center of People's Armed Police Forces, Tianjin, 300162, China., Wang S; Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin Medical University, Tianjin, 300070, China.; Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin Medical University, Tianjin, 300070, China., Shen Y; Department of Neurosurgery, Union Medicine Centre, The First Affiliated Hospital of Nankai University, Tianjin, 300121, China., Zhou Y; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China., Wei M; Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin Medical University, Tianjin, 300070, China., Yan H; Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin Medical University, Tianjin, 300070, China. yanhua20042007@sina.com.; Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Neurosurgical Institute, Tianjin Huanhu Hospital, Tianjin, 300350, China. yanhua20042007@sina.com.; Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin Medical University, Tianjin, 300070, China. yanhua20042007@sina.com.
Source:
Scientific reports [Sci Rep] 2025 Aug 19; Vol. 15 (1), pp. 30377. Date of Electronic Publication: 2025 Aug 19.
Publication Type:
Journal Article
Language:
English
Journal Info:
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Imprint Name(s):
Original Publication: London : Nature Publishing Group, copyright 2011-
MeSH Terms:
Carotid Artery, Internal*/surgery , Carotid Artery, Internal*/pathology , Reperfusion*/methods , Embolic Protection Devices* , Endovascular Procedures*/methods , Balloon Occlusion*/methods , Carotid Stenosis*/surgery , Carotid Stenosis*/therapy, Humans ; Male ; Female ; Aged ; Middle Aged ; Retrospective Studies ; Treatment Outcome ; China ; Stroke
References:
Stroke. 2018 Jan;49(1):232-235. (PMID: 29212743)
J Neurointerv Surg. 2015 Jun;7(6):412-7. (PMID: 24727131)
J Am Coll Cardiol. 2012 Apr 10;59(15):1383-9. (PMID: 22284330)
Cerebrovasc Dis. 2020;49(2):223-232. (PMID: 32335550)
Stroke. 2019 Feb;50(2):428-433. (PMID: 30580729)
Neuroradiology. 2015 Jun;57(6):589-98. (PMID: 25404414)
J Vasc Surg. 2001 Mar;33(3):504-9. (PMID: 11241119)
Stroke Vasc Interv Neurol. 2022 Sep;2(5):. (PMID: 36506814)
Neurol Sci. 2021 Jun;42(6):2301-2308. (PMID: 33037515)
Clin Neuroradiol. 2013 Sep;23(3):207-15. (PMID: 23354342)
Cerebrovasc Dis. 2016;42(5-6):387-394. (PMID: 27359223)
J Neurointerv Surg. 2018 Dec;10(12):1155-1160. (PMID: 29706606)
Exp Ther Med. 2020 Aug;20(2):1129-1136. (PMID: 32765661)
Neurol Med Chir (Tokyo). 2019 Sep 15;59(9):337-343. (PMID: 31281169)
Clin Radiol. 2023 Jun;78(6):451-458. (PMID: 36932006)
Stroke. 2012 Sep;43(9):2362-8. (PMID: 22811456)
Neurosurgery. 2011 Apr;68(4):1084-90; discussion 1091. (PMID: 21792107)
Stroke. 2011 Sep;42(9):2419-24. (PMID: 21757665)
J Neurol. 2022 Aug;269(8):4383-4395. (PMID: 35357557)
Stroke. 2013 Sep;44(9):2650-63. (PMID: 23920012)
Ther Adv Neurol Disord. 2022 Nov 21;15:17562864221136335. (PMID: 36437850)
Stroke. 2012 Jan;43(1):125-30. (PMID: 22034003)
Grant Information:
GWJJ20221001062 National Health Commission Capacity Building and Continuing Education Center Nervous System and Minimally Invasive Intervention Program; TJWJ2024ZD0063 Tianjin Health Science and Technology Project; TJWJ2022XK031 Tianjin Health Science and Technology Project Key Discipline Special Project
Contributed Indexing:
Keywords: ABGCEPD; Acute symptomatic isolated cervical internal carotid artery occlusion; Balloon guide catheter; Embolic protection device; Embolization to new territories; sICAO
Entry Date(s):
Date Created: 20250819 Date Completed: 20250820 Latest Revision: 20250822
Update Code:
20250822
PubMed Central ID:
PMC12365308
DOI:
10.1038/s41598-025-16491-7
PMID:
40830585
Database:
MEDLINE

Weitere Informationen

The optimal endovascular strategy for acute symptomatic isolated cervical internal carotid artery occlusion (sICAO) management remains unclear because of the anatomical complexity and high risk of distal embolization. This study looks into the safety, effectiveness, and outcomes of a novel Aspiration-Based Dual-Protection Strategy Under Proximal Balloon Occlusion and Distal Embolic Protection Device (ABGCEPD) for sICAO treatment. This retrospective study involved 65 patients with acute moderate-to-severe stroke who underwent endovascular treatment using ABGCEPD at three hospitals in China between January 2016 and December 2023. The primary outcome included successful reperfusion, defined as a modified Thrombolysis in Cerebral Infarction score ≥ 2b. A good outcome at discharge was defined as a modified 3-month Rankin Scale (mRS) score of 0 to 2 at 90 days. Secondary outcomes included mortality, symptomatic intracranial hemorrhage (sICH), and embolization to new territories (ENT). All 65 patients with sICAO were treated using ABGCEPD. The rate of successful reperfusion (modified Thrombolysis in Cerebral Infarction score ≥ T2b) was 92.9%, with a good clinical outcome attained by 60% of patients (90-day mRS 0-2). The incidence of sICH was 10.7%, mortality was 7.1%, and ENT was 7.0%. ABGCEPD is a feasible, safe, and efficient method for acute sICAO management. It may decrease the incidence of distal embolization during endovascular treatment.
(© 2025. The Author(s).)

Declarations. Competing interests: The authors declare no competing interests.