• Dynamical task switching in ce...

Treffer: Dynamical task switching in cellular computers

Title:
Dynamical task switching in cellular computers
Authors:
Goñi-Moreno, Angel, Cruz, Fernando de la, Rodríguez-Patón, Alfonso, Amos, Martyn
Contributors:
Universidad de Cantabria
Source:
Life, 2019, 9(1), 14
Publisher Information:
MDPI AG
Publication Year:
2019
Collection:
Universidad de Cantabria: UCrea
Subject Terms:
Synthetic Biology, Cellular Computing, Plasmids
Document Type:
Fachzeitschrift article in journal/newspaper
Language:
English
Relation:
https://doi.org/10.3390/life9010014; info:eu-repo/grantAgreement/AEI//TIN2016-81079-R/ES/INGENIERIA DE BIOCIRCUITOS PROGRAMABLES PARA COMPUTACION ANALOGICA, MULTICELULAR Y ESPACIAL/; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2017-86378-P/ES/SUPERIORIDAD DE LOS PLASMIDOS/; https://hdl.handle.net/10902/15868
DOI:
10.3390/life9010014
Availability:
https://hdl.handle.net/10902/15868
https://doi.org/10.3390/life9010014
Rights:
Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0/ ; openAccess
Accession Number:
edsbas.4A1073EF
Database:
BASE

Weitere Informationen

We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of computational simulations of our model, and discuss the potential for future work in this area. ; The work of A.G.-M. is supported by the SynBio3D (UK-EPSRC-EP/R019002/1) project of the UK Engineering and Physical Sciences Research Council and the BioRoboost (EU-H2020-BIOTEC-820699) Contract of the European Union. The work of AR-P is supported by the Spanish TIN2016-81079-R, (MINECO AEI/FEDER, EU) and Madrid Gov. project B2017/BMD-3691, InGEMICS-CM (FSE/FEDER, EU). Work in FdlC laboratory was financed by grant BFU2017-86378-P from the Ministry of Science and Technology (Spain).