Treffer: A multi-scale constraint programming model of alternative splicing regulation
Title:
A multi-scale constraint programming model of alternative splicing regulation
Authors:
Source:
Computational Systems BiologyTheoretical computer science. 325(1):3-24
Publisher Information:
Amsterdam: Elsevier, 2004.
Publication Year:
2004
Physical Description:
print, 25 ref
Original Material:
INIST-CNRS
Subject Terms:
Computer science, Informatique, Sciences exactes et technologie, Exact sciences and technology, Sciences et techniques communes, Sciences and techniques of general use, Mathematiques, Mathematics, Analyse mathématique, Mathematical analysis, Calcul des variations et contrôle optimal, Calculus of variations and optimal control, Sciences appliquees, Applied sciences, Informatique; automatique theorique; systemes, Computer science; control theory; systems, Informatique théorique, Theoretical computing, Automates. Machines abstraites. Machines de turing, Automata. Abstract machines. Turing machines, Algorithmique. Calculabilité. Arithmétique ordinateur, Algorithmics. Computability. Computer arithmetics, Sciences biologiques et medicales, Biological and medical sciences, Sciences biologiques fondamentales et appliquees. Psychologie, Fundamental and applied biological sciences. Psychology, Generalites, General aspects, Mathématiques biologiques. Statistiques. Modèles. Métrologie. Informatique en biologie (généralités), Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects), Lentivirus, Retroviridae, Virus, Biologie mathématique, Mathematical biology, Biología matemática, Donnée expérimentale, Experimental data, Dato experimental, Epissage alternatif, Alternative splicing, Empalme alternativo, Informatique théorique, Computer theory, Informática teórica, Modélisation, Modeling, Modelización, Programmation logique avec contrainte, Constraint logic programming, Programación lógica con restricción, RNA, Système hybride, Hybrid system, Sistema híbrido, Virus HIV1, HIV-1 virus, Virus immunodéficience humaine, Human immunodeficiency virus, Complexité combinatoire, Combinatorial complexity, Régulation épissage, Splicing regulation
Document Type:
Konferenz
Conference Paper
File Description:
text
Language:
English
Author Affiliations:
LORIA, Université Henri Poincaré, BP 239, 54506 Vandoeuvre-lès-Nancy, France
Laboratoire de Maturation des ARN et Enzymologie Moléculaire, UMR 7567 CNRS-UHP, BP 239, 54506 Vandoeuvre-lès-Nancy, France
INRIA Rhône-Alpes, Helix Project, 655 avenue de l'Europe, Montbonnot, 38334 Saint Ismier, France
Laboratoire de Maturation des ARN et Enzymologie Moléculaire, UMR 7567 CNRS-UHP, BP 239, 54506 Vandoeuvre-lès-Nancy, France
INRIA Rhône-Alpes, Helix Project, 655 avenue de l'Europe, Montbonnot, 38334 Saint Ismier, France
ISSN:
0304-3975
Rights:
Copyright 2004 INIST-CNRS
CC BY 4.0
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
CC BY 4.0
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Notes:
Biological sciences. Generalities. Modelling. Methods
Computer science; theoretical automation; systems
Generalities in biological sciences
Mathematics
Computer science; theoretical automation; systems
Generalities in biological sciences
Mathematics
Accession Number:
edscal.16145752
Database:
PASCAL Archive
Weitere Informationen
Alternative splicing is a key process in post-transcriptional regulation, by which different mature RNA can be obtained from the same premessenger RNA. The resulting combinatorial complexity contributes to biological diversity, especially in the case of the human immunodeficiency virus HIV-1. Using a constraint programming approach, we develop a model of the alternative splicing regulation in HIV-1. Our model integrates different scales (single site vs. multiple sites), and thus allows us to exploit several types of experimental data available to us.