• Interventions for branch retin...

Treffer: Interventions for branch retinal vein occlusion : An evidence-based systematic review

Title:
Interventions for branch retinal vein occlusion : An evidence-based systematic review
Authors:
MCINTOSH, Rachel L, MOHAMED, Quresh, SEANG MEI SAW, TIEN YIN WONG
Source:
Ophthalmology (Rochester, MN). 114(5):835-846
Publisher Information:
New York, NY: Elsevier, 2007.
Publication Year:
2007
Physical Description:
print, 51 ref
Original Material:
INIST-CNRS
Subject Terms:
Ophthalmology, Ophtalmologie, Sciences biologiques et medicales, Biological and medical sciences, Sciences medicales, Medical sciences, Ophtalmologie, Ophthalmology, Rétinopathies, Retinopathies, Divers, Miscellaneous, Appareil circulatoire pathologie, Cardiovascular disease, Aparato circulatorio patología, Oeil pathologie, Eye disease, Ojo patología, Rétinopathie, Retinopathy, Retinopatía, Vaisseau sanguin pathologie, Vascular disease, Vaso sanguíneo patología, Veine pathologie, Venous disease, Vena patología, Branche, Branch, Rama, Médecine factuelle, Evidence-based medicine, Medicina basada en pruebas, Ophtalmologie, Ophthalmology, Oftalmología, Revue systématique, Systematic review, Revisión sistemática, Thrombose veine centrale rétine, Central retinal vein occlusion, Trombosis de la vena central de la retina
Document Type:
Konferenz Conference Paper
File Description:
text
Language:
English
Author Affiliations:
Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
Royal Victorian Eye and Ear Hospital, Melbourne, Australia
Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Singapore Eye Research Institute, National University of Singapore, Singapore
ISSN:
0161-6420
Access URL:
http://pascal-francis.inist.fr/vibad/index.php?action=search&terms=18714586
Rights:
Copyright 2007 INIST-CNRS
CC BY 4.0
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Notes:
Ophthalmology
Accession Number:
edscal.18714586
Database:
PASCAL Archive

Weitere Informationen

Topic: To assess the evidence on interventions to improve visual acuity (VA) and to treat macular edema and/or neovascularization secondary to branch retinal vein occlusion (BRVO). Clinical Relevance: Branch retinal vein occlusion is the second most common retinal vascular disease. Methods/Literature Reviewed: English and non-English articles were retrieved using a keyword search of Medline (1966 onwards), Embase, the Cochrane Collaboration, the National Institute of Health Clinical Trials Database, and the Association for Research in Vision and Ophthalmology Annual Meeting Abstract Database (2003-2005). This was supplemented by hand searching references of review articles. Two investigators independently identified all randomized clinical trials (RCTs) with more than 3 months' follow-up. Results: From 4332 citations retrieved, 12 RCTs were identified. There were 5 RCTs on laser photocoagulation. Grid macular laser photocoagulation was effective in improving VA in 1 large multicenter RCT, the Branch Vein Occlusion Study (BVOS), but 2 smaller RCTs found no significant difference. The BVOS showed that scatter retinal laser photocoagulation was effective in preventing neovascularization and vitreous hemorrhage in patients with neovascularization, but a subsequent RCT found no significant effect. Randomized clinical trials evaluating intravitreal steroids (n = 2), hemodilution (n = 3), ticlopidine (n = 1), and troxerutin (n = 1) showed limited or no benefit. Conclusions: There is limited level I evidence for any interventions for BRVO. The BVOS showed that macular grid laser photocoagulation is an effective treatment for macular edema and improves vision in eyes with VA of 20/40 to 20/200, and that scatter laser photocoagulation can effectively treat neovascularization. The effectiveness of many new treatments is unsupported by current evidence.