• Validation of High-Performance...

Treffer: Validation of High-Performance Thin-Layer Chromatographic Methods for the Identification of Botanicals in a cGMP Environment

Title:
Validation of High-Performance Thin-Layer Chromatographic Methods for the Identification of Botanicals in a cGMP Environment
Authors:
REICH, Eike, SCHIBLI, Anne, DEBATT, Alison
Source:
Journal of AOAC International. 91(1):13-20
Publisher Information:
Gaithersburg, MD: AOAC International, 2008.
Publication Year:
2008
Physical Description:
print, 14 ref
Original Material:
INIST-CNRS
Subject Terms:
Food science technology, Sciences technologies alimentaires, Analytical chemistry, Chimie analytique, Sciences biologiques et medicales, Biological and medical sciences, Sciences biologiques fondamentales et appliquees. Psychologie, Fundamental and applied biological sciences. Psychology, Industries agroalimentaires, Food industries, Chromatographie, Chromatography, Cromatografía, Environnement, Environment, Medio ambiente, Haute performance, High performance, Alto rendimiento, Identification, Identificación, Méthode, Method, Método, Validation, Validación
Document Type:
Fachzeitschrift Article
File Description:
text
Language:
English
Author Affiliations:
CAMAG Laboratory, Sonnenmattstrasse 11, 4132 Muttenz, Switzerland
CAMAG Scientific Inc., 515 Cornelius Harnett Dr, Wilmington, NC 28401, United States
ISSN:
1060-3271
Access URL:
http://pascal-francis.inist.fr/vibad/index.php?action=search&terms=20081881
Rights:
Copyright 2008 INIST-CNRS
CC BY 4.0
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Notes:
Agrifood industries
Accession Number:
edscal.20081881
Database:
PASCAL Archive

Weitere Informationen

Current Good Manufacturing Practices (cGMP) for botanicals stipulates the use of appropriate methods for identification of raw materials. Due to natural variability, chemical analysis of plant material is a great challenge and requires special approaches. This paper presents a comprehensive proposal to the process of validating qualitative high-performance thin-layer chromatographic (HPTLC) methods, proving that such methods are suitable for the purpose. The steps of the validation process are discussed and illustrated with examples taken from a project aiming at validation of methods for identification of green tea leaf, ginseng root, eleuthero root, echinacea root, black cohosh rhizome, licorice root, kava root, milk thistle aerial parts, feverfew aerial parts, and ginger root. The appendix of the paper, which includes complete documentation and method write-up for those plants, is available on the J. AOAC Int. Website (http://www.atypon -link.com/AOAC/loi/jaoi ).